This lecture overviews the relation between AI and medical imaging and diagnosis. First, an in informative summary of “What is AI?” is presented, containing topics such as Symbolic AI, Data, Machine Learning (Clustering, Classification and Neural Networks). Topics that are related to book content creation, e.g., image processing, computer vision and natural language processing, are presented. The use of AI in proteomics (protein folding prediction) is also overviewed. The role of AI in medical diagnosis and education is also detailed. Finally, the creation of a medical data market is presented.